Substrate: Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))
Seq-ID: P02545 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-51248   SMAD3_HUMAN
MINT-3297814   1433Z_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 lamin filament,
nuclear envelope,
perinuclear region of cytoplasm		 muscle organ development,
positive regulation of cell aging
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 5       METPSQRRATRSGAQ PKC_group 8477740
LTP
0.20
 - -
0.86
 --
T 10  METPSQRRATRSGAQASSTP - 17081983
HTP
0.24
 - -
0.86
 --
S 12 ETPSQRRATRSGAQASSTPLS - 18669648
HTP
0.36
 - -
0.85
 --
S 18 RATRSGAQASSTPLSPTRITR - 18669648
HTP
0.02
 - -
0.73
 --
T 19 ATRSGAQASSTPLSPTRITRL CDK_group 7915280
LTP
0.98
 MOD_CDK_SPxK_1
 - -
0.72
 --
T 19 ATRSGAQASSTPLSPTRITRL - 17081983
HTP
0.98
 MOD_CDK_SPxK_1
 - -
0.72
 --
T 19 ATRSGAQASSTPLSPTRITRL - 16964243
HTP
0.98
 MOD_CDK_SPxK_1
 - -
0.72
 --
T 19 ATRSGAQASSTPLSPTRITRL - 18669648
HTP
0.98
 MOD_CDK_SPxK_1
 - -
0.72
 --
S 22 SGAQASSTPLSPTRITRLQEK CDK_group 7915280
LTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 17081983
HTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 16964243
HTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 17287340
HTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 18220336
HTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 18669648
HTP
0.97
 MOD_CDK_SPxK_1
 - -
0.71
 --
T 199 RRVDAENRLQTMKEELDFQKN PKC_group 8477740
LTP
1.00
 - COIL
0.47
 --
S 277 YSAKLDNARQSAERNSNLVGA - 17081983
HTP
1.00
 - COIL
0.61
 --
S 301 ELQQSRIRIDSLSAQLSQLQK - 18669648
HTP
1.00
 - COIL
0.43
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 15302935
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 16083285
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 17081983
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 16964243
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 18220336
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 18669648
HTP
1.00
 - -
0.78
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 7915280
LTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 15302935
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 16083285
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 17081983
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 16964243
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 18220336
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 18669648
HTP
1.00
 - -
0.81
 --
T 394 EERLRLSPSPTSQRSRGRASS - 18669648
HTP
0.03
 - -
0.83
 --
S 395 ERLRLSPSPTSQRSRGRASSH - 17081983
HTP
1.00
 - -
0.84
 --
S 395 ERLRLSPSPTSQRSRGRASSH - 16964243
HTP
1.00
 - -
0.84
 --
S 395 ERLRLSPSPTSQRSRGRASSH - 18669648
HTP
1.00
 - -
0.84
 --
S 398 RLSPSPTSQRSRGRASSHSSQ - 18669648
HTP
0.38
 - -
0.88
 --
S 403 PTSQRSRGRASSHSSQTQGGG PKC_group 7915280
LTP
1.00
 - -
0.90
 --
S 403 PTSQRSRGRASSHSSQTQGGG - 16083285
HTP
1.00
 - -
0.90
 --
S 404 TSQRSRGRASSHSSQTQGGGS PKC_group 7915280
LTP
1.00
 - -
0.89
 --
S 406 QRSRGRASSHSSQTQGGGSVT - 16083285
HTP
1.00
 - -
0.87
 --
S 407 RSRGRASSHSSQTQGGGSVTK - 16083285
HTP
1.00
 - -
0.85
 --
S 407 RSRGRASSHSSQTQGGGSVTK - 17081983
HTP
1.00
 - -
0.85
 --
T 409 RGRASSHSSQTQGGGSVTKKR - 16083285
HTP
0.03
 - -
0.83
 --
S 414 SHSSQTQGGGSVTKKRKLEST - 17081983
HTP
0.21
 - -
0.81
 --
T 416 SSQTQGGGSVTKKRKLESTES PKC_group 8477740
LTP
0.20
 - -
0.79
 --
S 423 GSVTKKRKLESTESRSSFSQH - 16083285
HTP
0.06
 - -
0.68
 --
T 424 SVTKKRKLESTESRSSFSQHA - 17081983
HTP
0.18
 - -
0.68
 --
S 458 EGKFVRLRNKSNEDQSMGNWQ - 18669648
HTP
1.00
 - IF_tail
0.55
 1IFR 22.13%
T 480 KRQNGDDPLLTYRFPPKFTLK PKC_group 8477740
LTP
0.09
 - IF_tail
0.51
 1IFR 29.45%
S 525 KAQNTWGCGNSLRTALINSTG - 8477740
LTP
0.17
 - IF_tail
0.41
 1IFR 33.61%
S 613 SGAQVGGPISSGSSASSVTVT - 18669648
HTP
 - - -
0.61
 --
S 615 AQVGGPISSGSSASSVTVTRS - 18669648
HTP
 - - -
0.58
 --
S 616 QVGGPISSGSSASSVTVTRSY - 18669648
HTP
 - - -
0.57
 --
S 619 GPISSGSSASSVTVTRSYRSV - 18669648
HTP
 - - -
0.55
 --
S 625 SSASSVTVTRSYRSVGGSGGG PKC_group 8477740
LTP
 - - -
0.56
 --
S 628 SSVTVTRSYRSVGGSGGGSFG - 17081983
HTP
 - - -
0.53
 --
S 628 SSVTVTRSYRSVGGSGGGSFG - 16964243
HTP
 - - -
0.53
 --
S 628 SSVTVTRSYRSVGGSGGGSFG - 18220336
HTP
 - - -
0.53
 --
S 628 SSVTVTRSYRSVGGSGGGSFG - 18669648
HTP
 - - -
0.53
 --
S 632 VTRSYRSVGGSGGGSFGDNLV - 16964243
HTP
 - - -
0.51
 --
S 632 VTRSYRSVGGSGGGSFGDNLV - 18220336
HTP
 - - -
0.51
 --
S 632 VTRSYRSVGGSGGGSFGDNLV - 18669648
HTP
 - - -
0.51
 --
S 636 YRSVGGSGGGSFGDNLVTRSY - 17081983
HTP
 - - -
0.47
 --
S 636 YRSVGGSGGGSFGDNLVTRSY - 16964243
HTP
 - - -
0.47
 --
S 636 YRSVGGSGGGSFGDNLVTRSY - 18669648
HTP
 - - -
0.47
 --
S 652 VTRSYLLGNSSPRTQSPQNCS - 18669648
HTP
 - - -
0.57
 --

Substrate: Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))
Seq-ID: P02545-2 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 lamin filament,
nuclear envelope,
perinuclear region of cytoplasm		 muscle organ development,
positive regulation of cell aging
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 12 ETPSQRRATRSGAQASSTPLS - 18669648
HTP
0.95
 - -
0.85
 --
S 18 RATRSGAQASSTPLSPTRITR - 18669648
HTP
0.29
 - -
0.73
 --
T 19 ATRSGAQASSTPLSPTRITRL - 18669648
HTP
0.27
 - -
0.72
 --
S 22 SGAQASSTPLSPTRITRLQEK - 18220336
HTP
0.98
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 18669648
HTP
0.98
 - -
0.71
 --
S 301 ELQQSRIRIDSLSAQLSQLQK - 18669648
HTP
1.00
 - COIL
0.43
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 18220336
HTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 18669648
HTP
1.00
 - -
0.78
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 18220336
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 18669648
HTP
1.00
 - -
0.81
 --
T 394 EERLRLSPSPTSQRSRGRASS - 18669648
HTP
0.03
 - -
0.83
 --
S 395 ERLRLSPSPTSQRSRGRASSH - 18669648
HTP
1.00
 - -
0.84
 --
S 398 RLSPSPTSQRSRGRASSHSSQ - 18669648
HTP
0.36
 - -
0.88
 --
S 458 EGKFVRLRNKSNEDQSMGNWQ - 18669648
HTP
1.00
 - IF_tail
0.54
 1IFR 22.13%

Substrate: Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))
Seq-ID: P48678 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 lamin filament,
nuclear envelope		 nuclear envelope organization,
sterol regulatory element binding protein nuclear translocation,
ventricular cardiac muscle cell development,
positive regulation of cell aging
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 5       METPSQRRATRSGAQ PKC_group 8477740
LTP
1.00
 - -
0.86
 --
S 12 ETPSQRRATRSGAQASSTPLS - 17242355
HTP
0.25
 - -
0.85
 --
T 19 ATRSGAQASSTPLSPTRITRL - 17242355
HTP
0.98
 - -
0.72
 --
S 22 SGAQASSTPLSPTRITRLQEK - 17242355
HTP
0.97
 - -
0.71
 --
S 22 SGAQASSTPLSPTRITRLQEK - 19144319
HTP
0.97
 - -
0.71
 --
T 199 RRVDAENRLQTLKEELDFQKN PKC_group 8477740
LTP
1.00
 - COIL
0.41
 --
S 390 LEGEEERLRLSPSPTSQRSRG CDK_group 1959608
LTP
1.00
 - -
0.78
 --
S 390 LEGEEERLRLSPSPTSQRSRG - 16452087
HTP
1.00
 - -
0.78
 --
S 392 GEEERLRLSPSPTSQRSRGRA - 16452087
HTP
1.00
 - -
0.81
 --
S 392 GEEERLRLSPSPTSQRSRGRA CDK_group 8477740
LTP
1.00
 - -
0.81
 --
S 404 TSQRSRGRASSHSSQSQGGGS p70S6K_group 1956339
LTP
1.00
 - -
0.89
 --
S 409 RGRASSHSSQSQGGGSVTKKR - 1959608
LTP
0.20
 - -
0.83
 --
T 416 SSQSQGGGSVTKKRKLESSES PKC_group 8477740
LTP
0.16
 - -
0.79
 --
T 480 RRQNGDDPLMTYRFPPKFTLK PKC_group 8477740
LTP
0.16
 - IF_tail
0.57
 --
S 525 KAQNTWGCGSSLRTALINSTG - 8477740
LTP
0.15
 - IF_tail
0.41
 --
S 546 EEVAMRKLVRSLTMVEDNEDD - 19144319
HTP
0.17
 - -
0.58
 --
S 633 VTRSFRSVGGSGGGSFGDNLV - 17242355
HTP
0.61
 - -
0.49
 --
S 637 FRSVGGSGGGSFGDNLVTRSY - 17242355
HTP
 - - -
0.45
 --
S 652 LVTRSYLLGNSSPRSQSSQNC PKC_alpha 8477740
LTP
 - - -
0.53
 --

Substrate: Lamin A/C (lamin A (70 kD lamin) (from PhosphoBase))
Seq-ID: ENSP00000357283 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity intermediate filament
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 277 YSAKLDNARQSAERNSNLVGA - 17081983
HTP
 - - COIL
0.61
 - medium

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